Scientific Researcher (f/m/d)

Application deadline: 31/05/2026

The Department of Nuclear Medicine is providing a Scientific Researcher (f/m/d) up to 85% for one Year for the Preclinical Nuclear Imaging group led by Prof. MD. PhD. T. Higuchi.

With its high-performance cyclotron and clean rooms, the Clinic and Polyclinic for Nuclear Medicine at University Hospital of Würzburg is one of the most modern facilities for GMP-compliant production of radioactive biomarkers in Germany. All diagnostic examinations including state-of-the-art hybrid imaging procedures (PET/CT, SPECT/CT) are offered. In the research group headed by Prof. MD. PhD. T. Higuchi, an international and interdisciplinary research team is engaged in the new development of novel imaging probes for cardiology, neurology and oncology. The research work takes place in the modern laboratories of the German Center for Heart Failure (DZHI). (https://www.ukw.de/nuklearmedizin/startseite/)

This work focuses on the preclinical evaluation of newly developed PET radiotracers for oncological applications. The aim is to assess tracer performance in both in vitro and in vivo settings, with emphasis on specificity, sensitivity, and translational potential.
In vitro studies will characterize binding affinity, cellular uptake, and target specificity across tumor cell lines. Complementary in vivo experiments in preclinical tumor models will evaluate biodistribution, pharmacokinetics, and tumor-to-background contrast using PET/CT imaging.
This approach is expected to identify promising tracer candidates and improve non-invasive tumor characterization, enabling earlier detection and more precise monitoring of treatment response in oncology.

• A modern and good equipped preclinical Research Laboratory
  
• A great international research team in a wide range in the work field
  
• The option for a Job ticket for public transport in Würzburg
• Milon-Cyrcel and other benefits

• Characterize the in vitro and in vivo radiotracer pharmacokinetics of novel tracers
• Performance of protein and tissue binding assays
• Performance of in vitro and in vivo analyses of stability and metabolites
• Optional PET imaging, Biodistributions and autoradiography process

• Biology, Biomedical or biochemistry background (M.Sc. or PhD)
• Experience in in vitro especially in the performance and concept of cellular Assays
• FELASA-B Certificate or equal certification for animal experimental work optional
• Fluent English in both speaking and writing is required
• Good IT Competence, Experience with Office, GraphPad
• Team player with communication skills
• Experience in working with radioisotopes is optional

• Anspruchsvolles, vielfältiges und entwicklungsfähiges Aufgabengebiet
• Attraktive Bezahlung nach TV-L inkl. Jahressonderzahlung
• Aus- und Weiterbildung in der eigenen Akademie
• Betriebliche Altersvorsorge
• Betriebskindertagesstätte mit verlängerten Öffnungszeiten
• Betriebssportangebote
• Flexible Arbeitszeiten dank Gleitzeitregelung
• Jobrad
• Mitarbeiter Angebote