PhD in Immunology and Immunotherapy (m/w/d)

  • Zentrum für Experimentelle Molekulare Medizin
  • 01.09.2024
  • Full-time
  • Temporary with possibility of extension

Application deadline: 31/07/2024

The research group of Experimental stem cell transplantation at the Department of Medicine II, University Hospital Würzburg invites applications for a

We offer

  • Attractive payment according to TV-L including company pension scheme and annual special payment
  • Wide-ranging further training and individual further training in our own academy
  • The opportunity to work on a fascinating scientific topic in an international research team
  • Continuous scientific mentoring and academic training
  • Training in the Graduate School of Life Science at the University of Würzburg

Your Tasks

  • Development of project: perform experiments, evaluate and quantify results ensuring the project evolves and fulfils the goals and work packages.
  • Produce written reports and draft papers.
  • Present your results at local meetings and national and international conferences.
  • Assist with training other researchers, including Masters' and undergraduate project students.

Applications are invited for a PhD student position with principal investigator Dr. Haroon Shaikh (Experimental stem cell transplantation) in the working group of Andreas Beilhack at the Department of Medicine II, University Hospital in Würzburg. Successful candidates will work in an interdisciplinary project utilizing T cell engagers for high precision immunotherapy in the context of leukemia and allogeneic hematopoietic stem cell transplantation.
Our research group aims to better understand tumor microenvironment and allogenic stem cell transplantation (allo-HCT) with a focus on cellular mechanism and interactions resulting in pro- or antiinflammatory responses (Shaikh H et al. 2021 Front immunol, Shaikh H et al. 2022 JCI Insight, Dahlhoff J et al. 2022 Leukemia, Chopra M et al. 2016 JEM, Ataide MA et al. 2022 Immunity). State-of-the-art preclinical animal models, primary leukemic tissue together with cutting-edge technologies including advanced microscopy (confocal, LSFM), cellular methods (flow cytometry) as well as RNA-seq approaches (i.e. bulk and single cell) as well as numerous molecular biotechnological methods such as gain- and loss-of-function assays are applied in our research.

Your Profile

  • Excellent Master´s degree in life science (or equivalent)
  • Sound knowledge and strong interest in immunology and cell biology
  • Experience with conditional knock out mice and animal handling
  • Fluent speaking and writing skills in English (German is not a must)
  • Motivation, reliability and dedication to work in an academic research lab are a must

Applicants with the following qualifications are preferred:

  • Hands-on knowledge of mouse models of cancer and/or autoimmunity
  • Immune cell isolation and in vitro culture methods
  • Experience with molecular, and biochemical standard lab methods
  • Experience with RNA -sequencing analysis (single-cell/bulk) and bioinformatics

This is what you can look forward to

  • Training and Continuing Education
  • Retirement Pension Plan
  • Collegiality
  • Sport and Fitness Options
  • Employee Events
  • Corporate Benefits

Become part of the team: Apply now!

Dr. Haroon Shaikh
AG Beilhack
Tel: +49931 201 27638

Remuneration is in accordance with the relevant collective agreements. Severely disabled applicants will be given preference if they are otherwise equally qualified.

The University Hospital of Würzburg (UKW) offers an innovative and excellent working environment in cutting-edge medicine. Here, employees benefit from state-of-the-art technology, extensive training and career opportunities as well as flexible working time models for an optimal work-life balance. We attach great importance to diversity and inclusion in order to create a respectful and supportive working environment. A strong sense of community and interdisciplinary collaboration are central to our way of working. Würzburg, a city with a high quality of life, offers a wide range of cultural and leisure activities as well as excellent educational opportunities. The UKW takes responsibility for the health of society and promotes an environment that focuses on ethical values and social commitment. Become part of our team and help shape the future of medicine.